Fig. 6

Therapeutic effect of CUR-loaded biomimetic formulations in vitro. a p-tau Elisa kit analysis of cellular total p-tau level after treated with different formulations in OA-treated HT22 cells. b Western blot and c quantification results for hyperphosphorylated tau at threonine 205 epitopes, serine 396 and 404 epitopes in HT22 cells. Statistical analysis was performed using a one-way ANOVA test, with *** indicating p < 0.001, ** indicating p < 0.01 and *indicating p < 0.05 compared to the OA group (n = 3 per group). Error bars represent standard deviation