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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Farnesal-loaded pH-sensitive polymeric micelles provided effective prevention and treatment on dental caries

Fig. 9

Effects of different treatments on the microarchitecture of molars in rats. Animals were treated with distilled water, 15% ethanol, farnesol, farnesal, chlorhexidine, blank PMs, Far-PMs and PPi-Far-PMs, respectively. After 5 weeks, the molars of rats were analyzed using high-resolution micro-computed tomography to obtain three-dimensional reconstruction pictures of the smooth-surface molars (a) and sulcal-surface molars (b). The bone mineral density (BMD, c) and bone volume per tissue volume (BV/TV, D) were quantitatively measured. Data were expressed as mean ± SD (n = 7). The Tamhane’s T2 test (*P < 0.05) was used to assess for treatment efficacy. Symbols represented statistical significance of the labeled groups with the group treated with distilled water (#P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001)

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