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Table 1 Grading criteria for skin irritation experiments

From: Flexible liposomal gel dual-loaded with all-trans retinoic acid and betamethasone for enhanced therapeutic efficiency of psoriasis

Erythema score

Expression

Edema scores

Expression

0

Non

0

Non

1

Slight

1

Slight

2

Obvious

2

Obvious

3

Severe

3

Severe edema (the skin bulges about 1 mm)

4

Purplish red spot with eschar

4

Severe edema (skin swelling over 1mm with enlargement)

  1. The total score of the skin irritation test was 8, and the rating was non-irritation (0–0.49), mild irritation (0.5–2.99), moderate irritation (3.0–5.99), and severe irritation (6.0–8.0)