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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: 808 nm-activable core@multishell upconverting nanoparticles with enhanced stability for efficient photodynamic therapy

Fig. 3

a Uptake of UC-PMA-RB,Ce6 (2 nM) by HeLa cells at different incubation times. b Viability studies of UC-PMA and UC-PMA-RB,Ce6 after 24 h of NPs incubation under dark conditions, and IC50 values. c Irradiation controls with untreated cells (only cells and laser) and cells loaded with UC-PMA (2.5 nM) after 3 h of incubation and different irradiation times using 5 or 10 W cm−2. d Impact on the cell viability of UC-PMA-PS (2.5 nM, 3 h of incubation) under different laser irradiances and different irradiation times. e Comparison in the viability impact of free PS and its combinations at a 250 nM, and the PS linked to the UCNPs incubated at 2.5 nM, under dark conditions, and after 20 min of irradiation with an 808 nm laser with a irradiance of 5 W cm−2

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