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Table 1 The IC50 values in chemosensitivity assay in 3D cell cultures of HO-8910PM cells

From: Three-dimensional culture and clinical drug responses of a highly metastatic human ovarian cancer HO-8910PM cells in nanofibrous microenvironments of three hydrogel biomaterials

Cell culture groups

Cisplatin

Paclitaxel

Conc. (μg/mL)

IC50 (μg/mL)

Conc. (μg/mL)

IC50 (μg/mL)

Matrigel

1–20

6.79a

2–50

12.44a

Collagen

1–20

4.87a,b

2–50

10.26a,b

RADA16

1–20

4.70a,b

2–50

10.72a,b

2D culture

1–20

2.11

2–50

6.79

  1. a(P < 0.01) compared with 2D cell culture
  2. b(P < 0.01) compared with Matrigel