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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Intra-articular delivery of celastrol by hollow mesoporous silica nanoparticles for pH-sensitive anti-inflammatory therapy against knee osteoarthritis

Fig. 4

Loading CSL with HMSNs improved the solubility of CSL and capped with Cs gives a pH-responsive property. Solubility and pH-responsive release of CSL, CSL@HMSNs and CSL@HMSNs-CS (CHC). The solubility of crystalline CSL and CSL@HMSNs in pH = 7.4 PBS (a). Solubility curve of CSL@HMSNs in different pH PBS (pH = 6.0, 6.8, 7.7) (b). Accumulative release curve of CSL@HMSNs-CS in different pH PBS (pH = 6.0, 6.8, 7.7) (c)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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