Table 1 Classification of cellular pathways affected by differentially expressed genes identified in SH-SY5Y cells as predicted by DAVID software
Gene ontology ID | Cellular pathway | Genes | FDR |
|---|---|---|---|
GASNGINAYLC | |||
 Up-regulated genes | |||
  GO.0008152 | Metabolic process | 7 | 0.0014 |
  GO.0006950 | Response to stress | 7 | 0.0001 |
  GO.0009605 | Response to external stimulus | 3 | 0.0006 |
  GO.0007399 | Nervous system development | 3 | 0.0081 |
 Down-regulated genes | |||
  GO.0006508 | Proteolysis | 3 | 0.0307 |
  GO.0030198 | Extracellular matrix organization | 2 | 0.0027 |
  GO.0007165 | Diseases of signal transduction | 2 | 0.0081 |
  GO.0090398 | Cellular senescence | 1 | 0.0003 |
SLWERLAYGIC | |||
 Up-regulated genes | |||
  GO.0044707 | Single-multicellular organism process | 10 | 0.0015 |
  GO.0006950 | Response to stress | 8 | 0.0004 |
  GO.0009653 | Anatomical structure morphogenesis | 4 | 0.0105 |
  GO.0007399 | Nervous system development | 3 | 0.0430 |
  GO.0048699 | Generation of neurons | 2 | 0.0266 |
 Down-regulated genes | |||
  GO.0051716 | Cellular response to stimulus | 6 | 0.0319 |
  GO.0035556 | Intracellular signal transduction | 3 | 0.0024 |
  GO.0007264 | Small GTPase mediated signal transduction | 2 | 0.0005 |