Table 2 Pharmacokinetic parameters of ORLN-PHI administered orally and PHI solution administered subcutaneously
From: “Oil-soluble” reversed lipid nanoparticles for oral insulin delivery
Parameters | ORLN-PHI (ig) | PHI solution (s.c) |
|---|---|---|
Cmax (μIU/mL) | 8.03 ± 2.68 | 15.49 ± 3.41 |
MRT (h) | 3.5 | 2.7 |
AUC0-8h ((μIU/mL) h) | 25.29 ± 4.85 | 44.08 ± 3.74 |
Frel (%) | 28.7% |