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Table 2 Necrosis rate and apoptotic rate of the RAW264.7 cells under the different treatments

From: A synergistic bactericidal effect of low-frequency and low-intensity ultrasound combined with levofloxacin-loaded PLGA nanoparticles on M. smegmatis in macrophages

Groups

N

Apoptosis rate

Necrosis rate

Control

6

3.30 ± 1.01

2.21 ± 0.21

LEV

6

6.60 ± 1.78*

2.28 ± 0.35

LEV-NPs

6

10.42 ± 0.84*#

4.20 ± 1.04*#

US

6

8.76 ± 0.78*

9.54 ± 0.88*#

LEV + US

6

15.54 ± 1.30*#

7.82 ± 044*#

LEV-NPs + US

6

21.25 ± 1.15*#

8.21 ± 0.66*#

  1. LEV: levofloxacin; LEV-NPs: levofloxacin-loaded PLGA nanoparticles; US: ultrasonic; SD: standard deviation
  2. Compared with the control, *P < 0.05; compared with the LEV, #P < 0.05. Data represent the mean ± SD