Fig. 5
Irradiation pretreatment strengthens the antitumor activity of PINPs@PM in vitro. a ROS staining of 4T1 cells phagocytosing PINPs@PM in the presence and absence of X-ray irradiation. The scale is 20 μm. b The temperature of PINPs@PM (30 μg/ml) upon excitation by NIR for different times. c The survival of 4T1 cells treated with PINPs@PM in the presence and absence of irradiation pretreatment. **, P < 0.01. d AO staining showing the damage of lysosome in 4T1 cells. White arrows indicate the representative cytoplasmic lysosome. The scale is 20 μm