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Table 1 IC50 values for Ru-1, TPP-PEG-biotin SAN, and Ru-1@TPP-PEG-biotin SANs against MCF-7 and HepG2 cancer cells

From: Multifunctional TPP-PEG-biotin self-assembled nanoparticle drug delivery-based combination therapeutic approach for co-targeting of GRP78 and lysosome

  

IC50 values (µM)

Cell lines

Ru-1

TPP-PEG-biotin SAN

Ru-1@TPP-PEG-biotin SAN

MCF-7

2.10*

4.74*

1.84

HepG2

3.01

5.92

1.55

  1. Cell viability was determined by MTT assay after 24 h incubation (mean of three independent experiments ± SD). * reported values [11, 12]
  2. The IC50 values of TPP-PEG-biotin SAN, and Ru-1@TPP-PEG-biotin SANs were acquired based upon MTT assay results under the light irradiation. The IC50 value of Ru-1 was obtained under the dark condition. Light dose: 660 nm, 30 mW/cm2, 20 min
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Journal of Nanobiotechnology

ISSN: 1477-3155

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