Fig. 5From: Enhanced oral delivery of insulin via the colon-targeted nanocomposite system of organoclay/glycol chitosan/Eudragit®S100Cellular transport of insulin with different formulations (a), and the effect of nanoparticles on the trans-epithelial electrical resistance (TEER) (b) in Caco-2 cells (mean ± SD, n = 3). TEER values were measured during incubation in the presence and absence of nanoparticles. After 4 h of incubation, the drug solution was replaced by fresh culture medium, and TEER value recovery was monitored over time. *p <0.05, compared to free insulin solutionBack to article page