Fig. 8
From: Loop-armed DNA tetrahedron nanoparticles for delivering antisense oligos into bacteria
Bacterial growth inhibitory effect of LP-Td-L by inhibiting the acpP gene in E. coli. a Colony counting of E. coli after treatment with different concentrations of Td-Lanti-acpP (0.1, 0.5, or 1 μM) with or without LP2000 for different times (1, 3 or 5 h). b Quantitative real-time PCR analysis of acpP mRNA levels after exposure to different concentrations of Td-Lanti-acpP or LP-Td-Lanti-acpP (0.1, 0.5, or 1 μM) for 3 h. Td-Lmis was used as a negative control to confirm specific gene inhibiting of ASOs. “*”: p < 0.05; “**”: p < 0.01; “***”: p < 0.001 versus control group