Table 1 Summary of representative NIR photoresponsive DDSs for cancer therapy
From: Near-infrared photoresponsive drug delivery nanosystems for cancer photo-chemotherapy
Classification | DDS | Photosensitive material | NIR light wavelength | Tumor model | Refs |
|---|---|---|---|---|---|
Photothermal responsive DDSs | CuS-DOX-MBA@PCM | Stearic acid, lauric acid | 808 | EAC | [57] |
DOX/MCN | DPPC | 808 | 4T1 | [58] | |
PAM/Pt@IcLipo | DPPC | 808 | 4T1 | [59] | |
DOX/ICG/PCM | Auric acid, stearic acid | 808 | HeLa | [60] | |
IR-780/LON liposome | DPPC | 808 | LL/2 | [61] | |
P(DPP-BT/DOX) | Lauric acid, stearic acid | 730 | HeLa | [62] | |
TENAB nanoparticles | Linoleic acid, stearyl alcohol | 808 | HeLa | [63] | |
DOX/DiR/ABC | Ammonium bicarbonate | 760 | 4T1 | [65] | |
DTX/Au/ABC | Ammonium bicarbonate | 808 | S180 | [66] | |
PD@BS | 1-Tetradecanol | 808 | MDA-MB-231 | [71] | |
Prussian blue/DOX/PCM | 1-Pentadecanol | 808 | HepG2 | [72] | |
UCNPs@ZrO2-Ce6/DOX/PCM | 1-Tetradecanol | 808 | U14 | [74] | |
HPDC | 1-Tetradecano | 808 | 4T1 | [75] | |
Photodynamic responsive DDSs | Biomimetic dimeric prodrug | Thioketal linker | 638 | HeLa | [86] |
CMSNR-B-PEG/G3-Pt | Bis-(alkylthio)alkene linker | 660 | 4T1 | [92] | |
PTS-DP | Thioketal linker | 670 | CT26 | [96] | |
β-CD/Ada-BODIPY/Ada-PTX | Aminoacrylate group | 660 | HeLa | [97] | |
DOX/CP-NI | 2-Nitroimidazole | 635 | HeLa | [98] | |
Ce6/TPZ liposomes | 2-Nitroimidazole | 670 | MCF-7 | [99] | |
SPN-prodrugs | Hypoxia-cleavable linker | 808 | 4T1 | [100] | |
Photoconversion responsive DDSs | UCNP/ACCh | Coumarin | 980 | S180 | [107] |
TTA-UC nanoparticles | Coumarin | 650 | 4T1 | [108] | |
UCNP/Pt(IV) | Pt(IV) | 980 | H22 | [110] | |
UCNP-Pt(IV)-polymer | Pt(IV) | 980 | U14 | [112] | |
UCNPs/DOX-TAT-HA | Azobenzene | 980 | HepG2 | [114] | |
UCNP-curcumin | Spiropyran | 980 | 4T1 | [115] | |
UCNP-RB-polymer | 2-Nitrobenzyl | 980 | TT | [116] |