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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Chitosan-miRNA functionalized microporous titanium oxide surfaces via a layer-by-layer approach with a sustained release profile for enhanced osteogenic activity

Fig. 5

a Fluorescence images of 40× (upper) and 120× (lower) showing the uptake of Cy3-labelled miRNAs (red) by cells after 24 h of culture on the CS-miRNA/HA PEM functionalized MAO surface: Cell nucleus was visualized using DAPI (blue) and membrane using DIO (green). b Downregulation of microRNA expression by 5 layers miRNA coating. ***p < 0.001 vs the CS-antimiR-control/HA PEM-functionalized MAO surface; ###p < 0.001 vs the CS-coated MAO surface; $$$p < 0.001 vs the naked MAO surface

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Journal of Nanobiotechnology

ISSN: 1477-3155

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