Fig. 7From: Chitosan-miRNA functionalized microporous titanium oxide surfaces via a layer-by-layer approach with a sustained release profile for enhanced osteogenic activityRelative expression of a ALP, b BMP, c Col1, d OCN, e OSX and f RUNX2 by MSCs cultured on different samples. After culturing in the growth medium for 24 h, the medium was changed to osteogenic medium for further culture of 3 and 7 days. All values are normalized to GAPDH. *, **, ***p < 0.05, 0.01 and 0.001 vs the naked MAO surface; #,##,###p < 0.05, 0.01 and 0.001 vs the CS-coated MAO surface; @@, @@@p < 0.01 and 0.001 vs the CS-antimiR-control/HA PEM-functionalized MAO surfaceBack to article page