Fig. 8
The ALP product and collagen secretion after 7 days of culture as well as the ECM mineralization after 14 days of culture: (a, a’ and a’’) the CS-antimiR-138/HA PEM-functionalized MAO surface, (b, b’ and b’’) the CS-antimiR-control/HA PEM-functionalized MAO surface, (c, c’ and c’’) the CS-coated MAO surface and (d, d’ and d’’) the naked MAO surface. The bottom panel shows the semi-quantitative results. ***p < 0.001 vs the naked MAO surface; ###p < 0.001 vs CS-coated MAO surface; &&&p < 0.001 vs the CS-antimiR-control/HA PEM-functionalized MAO surface