Fig. 6

The real-time fluorescence imaging of CIA mice. a Real-time fluorescence imaging of CIA mice after intravenous injection with free DID, DID/Lip/Dex, DID/Exo/Dex and DID/FPC-Exo/Dex, respectively (n = 3). b Ex vivo imaging of the plasma and organs at 24 h after intravenous injection. c Semi-quantitation of fluorescence intensity in joints. d Semi-quantitation of fluorescence intensity in joints in plasma and organs (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs mice injectedted with DID/FPC-Exo/Dex, ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 are mice injected with DID/Lip/Dex compared to DID/Exo/Dex)