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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Synergistic co-delivery of diacid metabolite of norcantharidin and ABT-737 based on folate-modified lipid bilayer-coated mesoporous silica nanoparticle against hepatic carcinoma

Fig. 5

a Tumor growth in H22 tumor-bearing mice treated with free drugs and nanoparticle samples after H22 cells were injected at day 0 (administered on days 1–14, and killed on day 15; n = 6). b H22 tumor-bearing mice weight change of free drugs and nanoparticle samples after H22 cells were injected at day 0 (administered on days 1–14, and killed on day 15; n = 6). Notes: In free drug groups, DM-NCTD, 2 mg/kg (i.v.); ABT-737, 50 mg/kg (i.p.); FA-LB(ABT-737)-(DM-NCTD@CHMSN) group dosage was calculated according to the contents of DM-NCTD (2 mg/kg, i.v.). **P < 0.01 vs FA-LB(ABT-737)-(DM-NCTD@CHMSN) group; ##P < 0.01, #P < 0.05 vs DM-NCTD + ABT-737 group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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