Fig. 3From: Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancerSpecificity of αHER2/PEG-NPs for HER2++ cancer cells. MCF7/HER2 (HER2++) (circle shape) and MCF7/neo1(HER2+/−) (square shape) cancer cells in 96-well plates were incubated with mPEG × HER2 (solid shape) and mPEG × DNS (hollow shape) modified with different contrast agents. After washing, bound contrast agents were detected by ELISA (n = 3, triplicate). Bars, SDBack to article page