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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Internal cross-linked polymeric nanoparticles with dual sensitivity for combination therapy of muscle-invasive bladder cancer

Fig. 5

Establishment of an orthotopic bladder cancer model in C57BL/6 mice and in vivo distribution of free IR780 and DOX&IR780@PEG-PCL-SS NPs. a The upper is the biodistribution of NPs in normal mouse. The below is the In vivo distribution of free IR780 and DOX&IR780@PEG-PCL-SS NPs in cancer mice. The right size is ex vivo imaging of NPs in lung, heart, liver, spleen, kidney and bladder of the mice. b Through small animal CT, a tumor is shown when the bladder of the mouse is filled with urine 7 days after MB49-luciferase cells inject into the bladder wall

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