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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Topically applicated curcumin/gelatin-blended nanofibrous mat inhibits pancreatic adenocarcinoma by increasing ROS production and endoplasmic reticulum stress mediated apoptosis

Fig. 4

Molecular mechanism study of nano- curcumin against pancreatic cancer. a Intracellular ROS levels of murine PDAC cells changed by the curcumin released from Cc/Glt NMs (error bar: standard deviation); b western blot analysis of the expression level changes of cleaved-caspase 3, phospho-PERK, BIP, phospho-elF2α and phospho-STAT3 in murine PDAC cells; and c western blot analysis of the expression level changes of cleaved-caspase 3, phospho-PERK, BIP and phospho-STAT3 in three types of human PDAC cells

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