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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Topically applicated curcumin/gelatin-blended nanofibrous mat inhibits pancreatic adenocarcinoma by increasing ROS production and endoplasmic reticulum stress mediated apoptosis

Fig. 5

Antitumor effects of curcumin/gelatin-blended nanofibrous mats in a mouse model of PDAC. a The flow diagram of the antitumor effect study of Cc/Glt NMs; b the tumor volume change over time with the Cc/Glt NMs or Glt NMs applied on day 14; c the photographs and statistical volume results of the PDAC tumors after Cc/Glt NMs or Glt NMs were applied for 14 days; d BrdU labeling of the tumor sections to detect the proliferation of active cells after 14 days of treatment with Cc/Glt NMs; e the phospho-STAT3 expression levels in the tumor after 14 days of treatment with Cc/Glt NMs; and f the BIP expression levels in the tumor after 14 days of treatment with Cc/Glt NMs. (error bar: standard deviation)

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