Fig. 2From: Hafnium (IV) oxide obtained by atomic layer deposition (ALD) technology promotes early osteogenesis via activation of Runx2-OPN-mir21A axis while inhibits osteoclasts activityTemporal dynamic of MC3T3 and 4B12 proliferation activity. Cells were cultivated under normal growth condition or in the presence of HfO2. Proliferation rate of MC3T3 and 4B12 was estimated using resazurin-based in vitro toxicology (TOX8) assay kit (a). Population doubling time (PDT) value of MC3T3 and 4B12 cells was determined using TOX8 assay results (b). Error bars represent the means ± SD. *p < 0.05, ***p < 0.001; Student’s t testBack to article page