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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Micelles self-assembled by 3-O-β-d-glucopyranosyl latycodigenin enhance cell membrane permeability, promote antibiotic pulmonary targeting and improve anti-infective efficacy

Fig. 2

GP-682 micelles enhanced cell membrane permeability in BEAS-2B cells. a Fluorescence confocal images of BEAS-2B cell uptake of FITC after 30 min preincubation with different concentrations of GP-682 micelles (10, 50, 100 μg/mL) and GPA-696 micelles (100 μg/mL). b The TEER of BEAS-2B cells cocultured with 100 μg/mL GP-682 micelles for 90 min and TEER of BEAS-2B cells removed from micelles at 30 min. c Flow cytometry intensity assay of BEAS-2B cell uptake of FITC at 30 min after pretreatment with 10, 50, and 100 μg/ml GP-682 micelles (left panel). The median fluorescence intensity (MFI) for each group as summarized in a bar graph (right panel). (Data are presented as means ± SD, n = 3. a, c, *P < 0.05, **P < 0.01, ***P < 0.001 compared to the FITC group, #p < 0.05 compared to the 100 μg/mL GPA-696 micelles group)

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