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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Alpha lipoic acid antagonizes cytotoxicity of cobalt nanoparticles by inhibiting ferroptosis-like cell death

Fig. 2

CoNPs treatment enhanced the level of intracellular ROS in Balb/3T3 cells, while ALA significantly inhibited the formation of ROS. The cells were exposed to CoNPs (400 μM) and ALA (200 μM) for 24 h. a–d The cells were visualized using a confocal laser scanning microscope. Each slide was scanned at ×20. The green fluorescence indicates the detected ROS production. e The fluorescent intensity of cells with different treatments. f The intracellular MDA concentration of cells with different treatments. All the data were expressed as mean ± SD of three independent experiments performed in triplicates. *p < 0.01, #p < 0.05 vs. control

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