Fig. 6
a TEM images from different locations of exosomes captured by the microfluidic device from PBS, FBS and whole blood. A negative control is also shown (Fe3O4NPs-EDC-NHS without the antibody). The blue arrow indicates the membrane of the exosome surrounded by the particles. b Exosomes are in indicated with blue circles and arrows whereas the magnetic nanoparticles covering them are signaled with red arrows. c High Magnification images to visualize the double membrane of the exosomes in the complexes. ELISA CD63 results indicating the number of exosomes captured. d Particle size analysis of the captured exosomes in the microfluidic device by NTA