Designed proteinoid polymers and nanoparticles encapsulating risperidone for enhanced antipsychotic activity

Table 1 Mw, Mn, Mp, PDI and optical activity of the proteinoids

Proteinoid^a	Mw^b (kDa)	Mn^b (kDa)	Mp^b (kDa)	PDI^c (kDa)	Optical activity [a] ^25 °C_D (°)^d
Prot.1	168.0	166.3	156.8	1.00	− 11.6
Prot.2	142.6	139.5	135.1	1.02	− 6.5
Prot.3	154.2	153.9	149.3	1.00	7.8
Prot.4	132.3	126.0	126.4	1.05	4.8

^aThe basic Prot.1,3 and acidic Prot.2,4 proteinoids were prepared at 140 and 180 °C, respectively
^bMolecular weights were measured by GPC, Mp is the molecular mass at the peak
^cPDI is the polydispersity index, given by Mw/Mn
^dSpecific optical rotation (c = 1 in H₂O at 25 °C)

ISSN: 1477-3155