|
Proteinoid NPs
|
Diameter (nm)
|
ζ-potential (mV)
|
DL (w/w%)
|
|---|
|
Prot.1
|
78 ± 4
|
12 ± 3
|
–
|
|
Prot.2
|
58 ± 2
|
− 10 ± 4
|
–
|
|
Prot.3
|
94 ± 7
|
12 ± 1
|
–
|
|
Prot.4
|
90 ± 4
|
− 8 ± 2
|
–
|
|
Prot.1/RSP
|
97 ± 2
|
13 ± 3
|
20 ± 0.1
|
|
Prot.2/RSP
|
86 ± 3
|
− 16 ± 1
|
20 ± 0.1
|
|
Prot.3/RSP
|
120 ± 5
|
13 ± 3
|
19 ± 0.4
|
|
Prot.4/RSP
|
122 ± 6
|
− 12 ± 2
|
19 ± 0.3
|
- Proteinoid particles were formed by a self-assembly process in aqueous 10 µM NaCl solution containing 1% DMSO. The initial RSP concentration was 20% w/w relative to the proteinoid. The hollow proteinoids and Prot./RSP NPs were PEGylated. The hydrodynamic diameter was measured by DLS, the ζ-potential was measured at pH = 7.4 by a ζ-potential analyzer, and the DL was measured by HPLC using a calibration curve of standard RSP solutions
