Fig. 6.

293-miR-XS-HER2 expressing both a ligand for tumor cell surface HER2 and a miRNA targeting HER2. a Accumulation of miR-HER2-E1 in stable cell lines. miR-HER2-E1 isolated from 293-miR-XS and 293-miR-XS-HER2 cell pellets and exosomes was quantified with normalization to the level of 18S rRNA. b The relative HER2 binding affinity of 293-miR-XS and 293-miR-XS-HER2 exosomes. The absorbance readings (OD 450 nm) are shown on the Y axis. Each result is presented as the mean ± standard deviation of three replicates. **p < 0.01