Fig. 4

Allosteric spherical nanoprobe assay performance for miRNA-150 detection. a The relative fluorescence intensity of the allosteric spherical nanoprobes with different miRNA-150 concentrations. b The linear relationship between the relative fluorescence intensity and the logarithm of miRNA-150 concentration over the range from 100 fM to 10 nM. c The results of real human serum samples for both NSCLC cancer patients (B) and healthy donors (A) with qRT-PCR (red) and the proposed method (blue). d The multipoint fluorescence scanning results on microarray corresponding to (a)