Synthesis and application of magnetic@layered double hydroxide as an anti-inflammatory drugs nanocarrier

Table 1 Comparison of different nanocarriers for Diclofenac sodium and Ibuprofen

Nanocarrier	Drug	Max. release (%)	Max. time	pH	Particle size	Refs.
Zn-Al layered double hydroxide (LDH)	Diclofenac sodium	80	60 h	7.4	632.6 nm	[41]
Sodium alginate/layered double hydroxides	Diclofenac sodium	99	8 h	7.4	ND	[42]
Ca–Al layered double hydroxide	Diclofenac sodium	84	400 min	4.6	1–3 µm	[43]
Zn–Al–NO₃-layered double hydroxides	Diclofenac sodium	98.4	6 h	6.8	132 ± 9 nm	[44]
IBU–LZH	Ibuprofen	77	1200 min	4.8	50–100 nm	[45]
Drug-LDH loaded PCL fibers	Ibuprofen	45	120 h	7.4	147 ± 37 nm	[46]
Alginate–zein/layered double hydroxide biocomposite	Ibuprofen	97	8 h	7.4	ND	[47]
Magnetic@layered double hydroxide	Diclofenac sodium	82	72 h	7.4	80–130 nm	This study
Magnetic@layered double hydroxide	Ibuprofen	96	72 h	7.4	80–130 nm	This study

ISSN: 1477-3155