Fig. 6

Antitumor effects of HK2 shRNA-loaded nanoparticles on chemosensitive A2780 tumor xenografts. The nude mice bearing cisplatin-sensitive A2780 tumor xenografts received an intravenous administration of saline, PP-shHK2, FPP-shHK2 or DFPP-shHK2 on days 1, 4, 7 and 10. a Tumor volume changes. b Tumor photos. c Tumor weights at the study end point. *P < 0.05, **P < 0.01 vs. control