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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Enhanced antitumor effects of follicle-stimulating hormone receptor-mediated hexokinase-2 depletion on ovarian cancer mediated by a shift in glucose metabolism

Fig. 8

Antitumor effects of DFPP-shHK2 on cisplatin-resistant A2780CP tumor xenografts. Nude mice bearing cisplatin-resistant A2780CP tumor xenografts received an intravenous administration of DFPP-shHK2 and cisplatin alone or in combination on days 1, 4, 7 and 10. a Tumor volume changes. b Tumor photos. c Tumor weights at the study end point. *P < 0.05, **P < 0.01 vs. control. d The expression of cisplatin resistance-associated proteins in A2780CP tumor xenografts according to immunohistochemistry (200X). e IHC staining of cleaved caspase-3 in A2780CP tumor xenografts (200X). f TUNEL staining in A2780CP tumor xenografts (200X)

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