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Table 3 Values of minimum inhibitory concentration (MIC) of voriconazole (VRC) and lipid polymer hybrid nanoparticles against different fungal strains

From: Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy and lung retention

Type of strain Fungal strain Labortory I.D. MIC (µg. mL−1)
VRC Blank LPH NPs Drug loaded LPH NPs
Laboratory strains Candida krusei CK 6258 0.23 14.84 0.11
Candida parapsilosis CP 22,019 0.05 14.84 0.03
Aspergillus flavus ATCC 204304 0.92 14.84 0.46
Aspergillus fumigatus ATCC 204305 0.92 14.84 0.23
Clinical isolates Aspergillus flavus R 4443 0.92 14.84 0.92
Aspergillus fumigatus R 4322 0.92 14.84 0.92
Aspergillus fumigatus R 4784 0.92 14.84 0.92
  1. LPH NPs lipid polymer hybrid nanoparticles, R Respiratory clinical isolate