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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Development of fluorescence/MR dual-modal manganese-nitrogen-doped carbon nanosheets as an efficient contrast agent for targeted ovarian carcinoma imaging

Fig. 10

In vivo toxicity test of Mn-N-CNSs@Anti-HE4: (A, a–f) Mouse serum biochemistry analysis before (0 day, control) and after injection of Mn-N-CNSs@Anti-HE4 (2.4 mM and 4.8 mM) for 1, 8, 22 days. B Histological images of the heart, liver, spleen lung, and kidneys of mice 1, 8 and 22 days post-intravenous injection of Mn-N-CNSs@Anti-HE4 (4.8 mM) and in control mice. The organs were sectioned and stained with hematoxylin and eosin (H&E) and observed under a light microscope, scale bar = 100 μm

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