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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Microtubule cytoskeleton-disrupting activity of MWCNTs: applications in cancer treatment

Fig. 1

Similarities between intracellular filaments and CNTs. a Tubulin protofilaments, actin microfilaments, and DNA have all been reported to interact with CNT. SWCNTs are very similar in size to DNA. This could explain their intrinsic clastogenic (DNA-breaking) effect. MWCNTs display diameters that vary between 4 and 25 nm. MWCNTs and microtubules share many morphological features. Ultrastructurally, MWCNTs and microtubules are very similar. Microtubule SEM image is adapted from Burgess et al. Nat. Comm. (2015) 6:8179

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