Fig. 11
The selectivity of mTHPC NPs against MeWo and FaDu cells. a–c Typical flow cytometry histograms of total (black), FaDu (blue) and MeWo (green) populations of cells from dissociated F5M5 spheroids treated with (a) Foslip®, (b) mTHPC-DCLs and (c) mTHPC-EVs. mTHPC concentration was 4.5 µM. Serum concentration – 6%. d The calculated ratio MFI of MeWo and FaDu cell populations in co-culture spheroids after 24 h of incubation with mTHPC-loaded NPs. Data presented as mean ± SD [n = 12–19; * p < 0.05 and *** p < 0.001, using one-sample t-test, µ = 1; ## p < 0.01, using ANOVA]