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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Hyaluronic acid-coated polymeric micelles with hydrogen peroxide scavenging to encapsulate statins for alleviating atherosclerosis

Fig. 2

CLSM images of RAW264.7 cells treated with PBS, Cy5-labeled PEMs and HPEMs with or without HA pretreatment and LO2 cells treated with Cy5-labeled HPEMs. Scale bar: 50 μm (a); cell viability of free SIM and SHPEMs against RAW264.7 for 24 h (b); cell viability of free SIM and SHPEMs with 4 μg/mL SIM for 24 h, 48 h and 72 h (c); cell viability of free SIM, SPEMs and SHPEMs (8 μg/mL SIM) for 4 h (d); quantitative analyses for ROS production of LPS-induced RAW264.7 cells treated with PBS, SIM, HPEMs and SHPEMs by flow cytometry (e) and cellular imaging. Scale bar: 100 μm (f). SIM simvastatin, HA hyaluronic acid, LPS lipopolysaccharide, SPEMs SIM-loaded amino-PEG-Ptyr-EO micelles, SHPEMs SIM-loaded HA-coated amino-PEG-Ptyr-EO micelles, HPEMs HA-coated amino-PEG-Ptyr-EO micelles

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