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Table 1 The biodistribution of different time points (6, 12, 18 and 24 h) after the injection of 99mTc-TEx-Cy7. Data are expressed as mean ± standard deviation (n = 3)

From: Hydrophobic insertion-based engineering of tumor cell-derived exosomes for SPECT/NIRF imaging of colon cancer

Tissues

99mTc-TEx-Cy7

6 h

12 h

18 h

24 h

Blood

1.85 ± 0.31

2.30 ± 0.37

1.21 ± 0.11

0.40 ± 0.03

Brain

0.07 ± 0.01

0.05 ± 0.01

0.04 ± 0.00

0.02 ± 0.01

Heart

0.49 ± 0.05

0.41 ± 0.04

0.46 ± 0.02

0.18 ± 0.05

Lung

2.23 ± 0.60

1.13 ± 0.12

1.11 ± 0.10

0.73 ± 0.41

Liver

14.29 ± 1.73

12.78 ± 1.45

7.28 ± 1.76

4.27 ± 0.31

Spleen

5.11 ± 0.94

3.32 ± 0.51

3.90 ± 0.50

1.33 ± 0.17

Kidney

7.35 ± 0.87

6.02 ± 0.30

5.85 ± 0.74

2.15 ± 0.72

Stomach

4.60 ± 1.54

0.86 ± 0.35

0.57 ± 0.06

0.24 ± 0.14

Intestine

0.77 ± 0.24

0.56 ± 0.08

0.42 ± 0.02

0.23 ± 0.05

Bone

1.29 ± 0.33

0.94 ± 0.13

0.75 ± 0.14

0.40 ± 0.13

Muscle

0.25 ± 0.05

0.21 ± 0.01

0.18 ± 0.02

0.11 ± 0.06

Tumor

0.80 ± 0.05

0.76 ± 0.13

1.46 ± 0.06

0.38 ± 0.02