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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Preclinical development of a novel CD47 nanobody with less toxicity and enhanced anti-cancer therapeutic potential

Fig. 5

Large scale production of HuNb1-IgG4 in CHO-S cells expression system. a The viable cell density (VCD) and the viability were detected. b The protein titer was determined within 14Ā days. c The lactic acid (Lac) and NH4+ produced during the culture process. d The thermal stability of HuNb1-IgG4 was detected by SEC-HPLC detection. The experiments were performed in triplicate and one representative experiment was shown

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