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Table 2 Pharmacokinetic parameters of coumarin 6 (C6) after oral administration of C6 in the different formulations to rats (Mean ± SD, n = 4)

From: Ternary nanocomposite carriers based on organic clay-lipid vesicles as an effective colon-targeted drug delivery system: preparation and in vitro/in vivo characterization

ParametersControl (C6 solution)C6-LipAC-C6-LipEAC-C6-Lip
Cmax (ng/mL)11.3 ± 1.4610.1 ± 2.088.0 ± 4.37.4 ± 1.3
Tmax (h)2.01.6 ± 0.54.0 ± 2.37.8 ± 10.9
AUC (ng h/mL)91.8 ± 21.097.0 ± 18.999.7 ± 38.499.9 ± 17.7