Skip to main content

Table 2 Pharmacokinetic parameters of coumarin 6 (C6) after oral administration of C6 in the different formulations to rats (Mean ± SD, n = 4)

From: Ternary nanocomposite carriers based on organic clay-lipid vesicles as an effective colon-targeted drug delivery system: preparation and in vitro/in vivo characterization

Parameters

Control (C6 solution)

C6-Lip

AC-C6-Lip

EAC-C6-Lip

Cmax (ng/mL)

11.3 ± 1.46

10.1 ± 2.08

8.0 ± 4.3

7.4 ± 1.3

Tmax (h)

2.0

1.6 ± 0.5

4.0 ± 2.3

7.8 ± 10.9

AUC (ng h/mL)

91.8 ± 21.0

97.0 ± 18.9

99.7 ± 38.4

99.9 ± 17.7