Fig. 4
The Ca2+ mobilization and functional change of fMLF-activated neutrophils. a Fluo-3/AM-labeled neutrophils were treated with free OA and OA-loaded nanocarriers for 5 min. Next, the cells were activated by fMLF. The [Ca2+]i-time curves are shown. b Peak calcium concentration ([Ca2+]i) traces are shown. c Reduction of the time taken to decline to half of its peak values (t1/2) are shown. All data represent mean ± SEM (n = 6). *p < 0.05, **p < 0.01 as compared to fMLF-activated group without OA intervention