Fig. 8
From: Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
Dystrophin expression in different muscles and serum study of mdx mice (aged 4–5 weeks) 2 weeks after systemic administration of PMO with TAPs. Each mouse was injected with 1 mg PMOE23 with and without TAP (0.5 mg). a Immunohistochemistry with antibody P7 for the detection of dystrophin (original magnification ×100; scale bar 200 µm). b Percentage of dystrophin-positive fibers in different muscle tissues (mean ± SD, n = 5, Two-tailed t-test, *p ≤ 0.05 compared with 1 mg PMO)