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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Protein liposomes-mediated targeted acetylcholinesterase gene delivery for effective liver cancer therapy

Fig. 1

Diagrammatic drawing depicting the preparation and evaluation of Tf-PL/AChE. Gene-carrying transferrin liposome preparation procedure (a) and delivery strategy of transferrin liposome-carrying gene-targeted transferrin receptor-positive cells (b). The ‘proteoliposome’ interacts with the surface TfR of the targeted cell (1), and then enters the cytoplasm by endocytosis (2), released by lysosomal digestion (3), transient expression in the cytoplasm (4)

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