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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids

Fig. 10

Effect of siEphA2 complexes co-administered with JIB-04 on KDM4A and EphA2 mRNA expression in PC-3. Bar plots showing the changes in KDM4A (a) and EphA2 (b) mRNA expression levels determined by qRT-PCR. 18S rRNA was used as a reference gene. The results are given as mean ± SEM. Asterisks represent statistical significance (UT: Untreated control, ns: not significant, *p < 0.05, ***p < 0.001, one-way ANOVA followed by Tukey’s test, n = 3)

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