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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids

Fig. 6

Gene silencing efficiency and cytotoxicity of siEphA2 complexes in DU145 and PC-3 cells (48 h). a, b Bar plots showing the changes in EphA2 mRNA expression levels determined by qRT-PCR. 18S rRNA was used as a reference gene. c, d Representative Western blot images and densitometric analysis of EphA2 protein expression levels. β-actin was used as a loading control. e, f Bar plots showing the effect of cSLNs and their complexes on cell viability. The results are given as mean ± SEM. Asterisks represent statistical significance (UT: Untreated control, ns: not significant, ***p < 0.001, one-way ANOVA followed by Tukey’s test, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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