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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids

Fig. 9

Effect of siEphA2 complexes co-administered with JIB-04 on colony formation ability of PC-3 cells. Representative images (a) and bar plots (b) of PC-3 colonies after 10 days of incubation. Image processing (thresholding and background subtraction) was done using ImageJ. Colony Area plugin of ImageJ was used to automatically quantify the intensity of colonies. The results are given as the mean ± SEM. Asterisks represent statistical significance (UT: Untreated control, ns: not significant, *p < 0.05, **p < 0.01, one-way ANOVA followed by Tukey’s test, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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