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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Highly stable organic photothermal agent based on near-infrared-II fluorophores for tumor treatment

Fig. 2

Stability exploration of NIR998 NPs. a, b are absorption and emission spectra of NIR998 (10 μM) in DMSO and NIR998 NPs (10 μM) in PBS, respectively. The emission spectra were acquired under excitation at 808 nm with same absorption. c Thermal cycling stability of ICG NPs (20 μM) and NIR998 NPs (20 μM) during seven heating and cooling circles (808 nm, 0.5 W cm−2). d The antiphotobleaching of NIR998 NPs (20 μM) and ICG NPs (20 μM). I/I0 was the ratio of the maximal absorption of dyes after and before irradiation (808 nm, 0.5 W cm−2) with time. Inset: Images of NIR998 NPs and ICG NPs solutions under various irradiation times, respectively. e ONOO or H2O2-dependent I/I0 change. I/I0 was the ratio of the absorption of NIR998 NPs plus ONOO or H2O2 solutions and NIR998 NPs solutions at 859 nm, respectively. f pH-dependent ApH/ApH=7.4 changes. ApH and ApH=7.4 represented the absorption of NIR998 NPs (859 nm) in PBS with different pH value, respectively

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