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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: pH-responsive delivery vehicle based on RGD-modified polydopamine-paclitaxel-loaded poly (3-hydroxybutyrate-co-3-hydroxyvalerate) nanoparticles for targeted therapy in hepatocellular carcinoma

Fig. 8

a Schematic illustration of the tumor suppression experiment. b The changes of tumor volumes curve. c Body weight of mice was measured during the 14 observation days in different groups. d Tumor weight of mice after treatment with saline, raw PTX and RGD-PDA-PHBV-PTX-NPs (data shown as means ± SD, n = 5, one way ANOVA, *p < 0.05, **p < 0.01, ***p < 0.001). e Images of excised tumors after treatment with different formulations. f H&E staining of tissues. Scale bar: 200 μm. PHBV, ploy (3-hydroxybutyrate-co-3-hydroxyvalerate); PTX, paclitaxel; PDA, polydopamine; NPs, nanoparticles

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